Duke continued the nations longest home court winning streak winning its 23rd straight game in Cameron Indoor Stadium.
The Blue Devils won their 75th straight home game against an unranked opponent.
With her four blocks on the night, Chante Black moved into a tie for third place on Duke's all-time blocked shots list with 151. She tied Iciss Tillis and moved past Alana Beard (149). Black also moved into a tie for 23rd on the ACC all-time blocks list.
The Blue Devils won their fourth straight and 11th out of the last 12 games against FSU.
Sophomore Bridgette Mitchell came off the bench to provide a spark scoring a season-high 10 points to go along with five rebounds and a season-high four assists in 15 minutes.
Duke forced 25 Florida State turnovers and allowed only six assists. FSU scored a season-low 38 points.
Florida State's 38 points is the lowest point total allowed against an ACC opponent since Duke held Wake Forest to 38 points on Feb. 13, 2000. FSU's 38 points is the fewest scored by the Seminoles since Jan. 26, 1997 when they scored 36 at N.C. State. Duke held FSU to a season-low 23.4.
As a team, Duke hit 1-of-12 from three-point land on the night with Emily Waner hitting her only attempt.
Duke improves to 6-0 at home this season.
All 11 Blue Devils who played scored on the night.
Junior Carrem Gay posted a career-high seven steals to go along five points, seven rebounds, one block and one assist.
By hitting 9-of-11 field goals on the night, Chante Black has now hit 21 out of her last 27 field goal attempts. Duke won its 15th straight ACC home opener.
The Blue Devils have now won 16 straight ACC games and 87 out of the last 92 ACC contests.
With her three-pointer with 0:33 left, senior Emily Waner continued Duke's 97-game streak with at least one three-pointer.
As a team, Duke blocked seven shots in the first half and went on to finish the game with 11.
The Blue Devils totaled a 52-18 points in the paint advantage.
After hitting 5-of-6 three-pointers at Miami in the last game, senior Wanisha Smith missed all nine of her shot attempts in the contest and finished with one point. She also had four rebounds and two assists in 24 minutes.
Junior Chante Black quickly registered double-figure points as she posted 10 points in the first six and a half minutes of play (13:27 mark). She went on to total 15 first half points and finished the game with 19. It marked the 14th time out of 16 games Black has posted double-figure points this season. She also had nine rebounds, four blocks and two assists.
Duke held a 57-45 rebounding advantage marking the fifth straight game the Blue Devils have outrebounded their opponent.
Sophomore Keturah Jackson left at the 5:39 mark of the first half with a hyperextended left knee injury. She played seven minutes in the first stanza scoring two points, grabbing two steals and one rebound. She returned to the game in the second half and played a total of 11 minutes.
Duke will next travel to College Park, Md., for a Monday, Jan. 11 contest at fourth-ranked Maryland (19-1).